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The Ensembl Variant Effect Predictor predicts the functional effects of genomic variants

active 2025-04-062026-06-25 (UTC)

Partial coverage11,215 / 11,907 hourly files (94%) · 2 absent upstream · 690 failed, retryable2025-04-012026-08-10 (UTC)— sampled evenly across the window, so rankings and trends hold; absolute counts scale up.
Events
379
Pushes
26
Pull requests
20
Issues
84
Stars
28
Forks
10

Activity over time

Daily event counts in the loaded window

Line chart, 446 days from 2025-04-06 to 2026-06-25. Pushes: 26 total, peak 3 in a day. Pull requests: 20 total, peak 2 in a day. Issues: 84 total, peak 5 in a day. Comments: 177 total, peak 7 in a day. Stars: 28 total, peak 1 in a day.

  • Pushes
  • Pull requests
  • Issues
  • Comments
  • Stars

Stars, PRs, issues and forks are under-captured in the later part of this window. GH Archive progressively stopped capturing non-push events during 2026 — −95% or worse by the end of the window. Every series here except Pushes fades for that reason, so a decline above reflects the archive, not this repository. Pushes stay reliable throughout, so read them, and the contributor counts derived from them, as the real signal. Data health has the measurements.

Top contributors

Pushes, PRs, issues, reviews and comments — stars and forks excluded, so this is contribution rather than popularity

Recent activity

Latest issues, pull requests and releases

  • Issue#2016ainefairbrother2026-06-25 17:47
    Issue Feedback on HGVS Nomenclature in Annotation Results
  • Issue comment#2002harsh-shukla2026-05-06 16:30
    Misannotation of a variants
  • Issue comment#2007Karthik-Tempus2026-05-03 14:59
    No recent releases
  • Issue#2007Karthik-Tempus2026-04-30 18:14
    No recent releases
  • Issue#2003ainefairbrother2026-04-30 08:14
    Failed to annotate with VEP when converting physical positions in a VCF file from hg19 to hg38 by CrossMap.
  • Issue#2005jinghengchen2026-04-24 17:33
    Failure to run VEP on certain variants
  • Issue comment#1984nakib1032026-04-07 19:32
    HGVSg and HGVSc notation generated by the REST API response are incorrect for some variants
  • Issue comment#1984nakib1032026-03-18 13:46
    HGVSg and HGVSc notation generated by the REST API response are incorrect for some variants
  • Issue comment#1972soliton-2026-03-06 16:26
    Handle white space in input path
  • Issue comment#1971ainefairbrother2026-03-06 10:05
    Cache param in VCF header line metadata leaks infrastructure details
  • Issue comment#1977Karthik-Tempus2026-02-25 16:55
    VEP (GRCh37 REST) is not annotating HGVSc for variants that span the region outside and within a transcript
  • Issue#1979ypradat2026-02-25 15:33
    CADD plugin WARNING: no match for ref
  • Issue comment#1976nakib1032026-02-25 12:18
    VEP (GRCh37 REST) did not annotate some of the overlapping transcripts/genes for a variant
  • Issue comment#1980likhitha-surapaneni2026-02-25 10:48
    clinvar_somatic_classification not showing any Somatic annotation?
  • Issue#1980likhitha-surapaneni2026-02-25 10:47
    clinvar_somatic_classification not showing any Somatic annotation?
  • Issue#1979likhitha-surapaneni2026-02-24 06:04
    Mysterious WARNING: no match for ref
  • Issue#1976Karthik-Tempus2026-02-19 15:58
    VEP (GRCh37 REST) did not annotate some of the overlapping transcripts/genes for a variant
  • Issue comment#1975nakib1032026-02-17 16:36
    docker container does not have the neccessary dependencies to run `INSTALL.pl` with `--USE_HTTPS_PROTO`
  • Issue#1975alkc2026-02-17 09:08
    docker container does not have the neccessary dependencies to run `INSTALL.pl` with `--USE_HTTPS_PROTO`
  • Pull request#1973ainefairbrother2026-02-12 16:20
  • Issue comment#1774ramprasadn2026-02-10 19:01
    Missing annotations for BND variants.
  • Issue comment#1964hienbio2026-02-10 08:54
    substr outside of string at 1342
  • Issue comment#1964hienbio2026-02-06 10:54
    substr outside of string at 1342
  • Pull request#1970likhitha-surapaneni2026-02-04 11:39
  • Issue comment#1879ainefairbrother2026-02-04 11:38
    Variant not being annotated

Totals cover only the window loaded into ClickHouse and count events, not GitHub's lifetime totals — 28 stars here means stars gained during the window, not the repo's star count.