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R package for performing 2-sample MR using MR-Base database; this fork aims to add `find_proxy` function for local outcome

active 2023-12-252026-07-28 (UTC)

Partial coverage18,088 / 23,154 hourly files (78%) · 2 absent upstream · 5,064 failed, retryable2023-12-212026-08-12 (UTC)— sampled evenly across the window, so rankings and trends hold; absolute counts scale up.
Events
589
Pushes
64
Pull requests
38
Issues
125
Stars
130
Forks
20

Activity over time

Daily event counts in the loaded window

Line chart, 947 days from 2023-12-25 to 2026-07-28. Pushes: 64 total, peak 5 in a day. Pull requests: 38 total, peak 2 in a day. Issues: 125 total, peak 33 in a day. Comments: 192 total, peak 7 in a day. Stars: 130 total, peak 3 in a day.

  • Pushes
  • Pull requests
  • Issues
  • Comments
  • Stars

Stars, PRs, issues and forks are under-captured in the later part of this window. GH Archive progressively stopped capturing non-push events during 2026 — −95% or worse by the end of the window. Every series here except Pushes fades for that reason, so a decline above reflects the archive, not this repository. Pushes stay reliable throughout, so read them, and the contributor counts derived from them, as the real signal. Data health has the measurements.

Top contributors

Pushes, PRs, issues, reviews and comments — stars and forks excluded, so this is contribution rather than popularity

Recent activity

Latest issues, pull requests and releases

  • Issue#654remlapmot2026-03-25 08:13
    [BUG]: Each startup loading of the TwoSampleMR takes 2 minutes.
  • Pull request#672remlapmot2026-02-26 09:27
  • Releaseremlapmot2026-02-24 10:31
    TwoSampleMR 0.7.0
  • Issue#670j-brody2026-02-23 17:20
    [BUG]: inferred p-value calculation is missing a factor of 2
  • Pull request#668remlapmot2025-12-17 07:01
  • Pull request#668remlapmot2025-12-17 06:51
  • Issue comment#665remlapmot2025-12-16 07:37
    [BUG]: not possible to specify r2 value for clumping using extract_instruments() but possible within read_exposure_data()
  • Issue comment#662remlapmot2025-12-15 13:20
    Why are they different?
  • Issue comment#662remlapmot2025-12-15 13:17
    Why are they different?
  • Releaseremlapmot2025-12-15 13:16
    TwoSampleMR 0.6.27
  • Issue#659al3xjwood2025-11-24 10:05
    Allow specification of r2 for read_exposure_data()
  • Issue#658DengBopinghrb2025-11-10 08:01
    [BUG]: Something is wrong when I run the "extract_outcome_data" function in the "Example 4. Effect of BMI on 103 diseases" session of the guide, details are below
  • Issue#658DengBopinghrb2025-11-10 08:01
    [BUG]: Something is wrong when I run the "extract_outcome_data" function in the "Example 4. Effect of BMI on 103 diseases" session of the guide, details are below
  • Pull request#656remlapmot2025-10-31 15:11
  • Pull request#653remlapmot2025-10-25 06:10
  • Issue comment#652Ewan-Simpson2025-09-25 04:19
    LD clump using local ref file in mv_extract_exposures_local() function
  • Issue#652Ewan-Simpson2025-09-25 04:19
    LD clump using local ref file in mv_extract_exposures_local() function
  • Issue#652Ewan-Simpson2025-09-24 05:55
    LD clump using local ref file in mv_extract_exposures_local() function
  • Pull request#651remlapmot2025-09-16 09:04
  • Issue comment#30jessica-lundin-sage2025-09-10 23:33
    Error when attempting to update to v0.4.9
  • Releaseremlapmot2025-08-27 10:42
    TwoSampleMR 0.6.22
  • Pull request#650remlapmot2025-08-27 10:42
  • Pull request#650remlapmot2025-08-27 10:19
  • Issue comment#647songlyzz2025-08-22 06:24
    [BUG]: Clumping for large size
  • Issue comment#648remlapmot2025-08-21 07:57
    Unable to extract outcome data after user merges multiple instrument SNPs

Totals cover only the window loaded into ClickHouse and count events, not GitHub's lifetime totals — 130 stars here means stars gained during the window, not the repo's star count.