Directed evolution of proteins in sequence space with gradients
active 2023-10-30 → 2025-11-18 (UTC)
Activity over time
Daily event counts in the loaded window
Line chart, 751 days from 2023-10-30 to 2025-11-18. Pushes: 21 total, peak 9 in a day. Pull requests: 9 total, peak 5 in a day. Issues: 9 total, peak 3 in a day. Comments: 14 total, peak 3 in a day. Stars: 47 total, peak 3 in a day.
- Pushes
- Pull requests
- Issues
- Comments
- Stars
Stars, PRs, issues and forks are under-captured in the later part of this window. GH Archive progressively stopped capturing non-push events during 2026 — −95% or worse by the end of the window. Every series here except Pushes fades for that reason, so a decline above reflects the archive, not this repository. Pushes stay reliable throughout, so read them, and the contributor counts derived from them, as the real signal. Data health has the measurements.
Top contributors
Pushes, PRs, issues, reviews and comments — stars and forks excluded, so this is contribution rather than popularity
| Contributor | Contributions | Pushes | PRs | Comments |
|---|---|---|---|---|
| pemami4911 | 45 | 21 | 8 | 10 |
| anonimoustt | 5 | 0 | 0 | 3 |
| Amelie-Schreiber | 2 | 0 | 0 | 1 |
| KrajShuffle | 1 | 0 | 0 | 0 |
| hazemessamm | 1 | 0 | 1 | 0 |
| willfinnigan | 1 | 0 | 0 | 0 |
Recent activity
Latest issues, pull requests and releases
- Issue comment#16pemami49112025-10-18 23:29handled the case for T5 tokenizers
- Pull request#16hazemessamm2025-09-18 18:18
- Issue comment#15pemami49112025-02-09 05:07Fix sampler.py issues creating sequence-score mismatches
- Issue#13willfinnigan2024-10-18 16:05ESM fitness doesn't match with esm fitness from other method
- Issue#12KrajShuffle2024-09-06 20:08Viability of Extending Approach to Antibodies
- Pull request#11pemami49112024-08-06 05:25
- Pull request#11pemami49112024-08-06 05:25
- Pull request#8pemami49112024-08-06 05:19
- Pull request#10pemami49112024-08-06 05:19
- Pull request#10pemami49112024-08-06 05:18
- Issue#9pemami49112024-08-06 03:35Out of memory issues
- Issue#4pemami49112024-07-10 23:06Weight of Sequence
- Issue comment#3pemami49112024-07-10 23:06is it possible to get the importance score of the protein sequence?
- Issue#3pemami49112024-07-10 23:06is it possible to get the importance score of the protein sequence?
- Issue comment#2pemami49112024-07-10 23:01Using Masked Marginal Score for ESM-2 as a Scoring Method
- Issue#2pemami49112024-07-10 23:01Using Masked Marginal Score for ESM-2 as a Scoring Method
- Releasepemami49112024-07-10 22:58v0.2
- Pull request#7pemami49112024-07-10 22:03
- Issue comment#7pemami49112024-07-10 22:02Flexible variant scoring
- Pull request#7pemami49112024-06-26 17:19
- Pull request#6pemami49112024-06-14 16:52
- Issue comment#3anonimoustt2024-02-13 03:04is it possible to get the importance score of the protein sequence?
- Issue comment#3anonimoustt2024-02-11 00:55is it possible to get the importance score of the protein sequence?
- Issue comment#3pemami49112024-02-10 21:08is it possible to get the importance score of the protein sequence?
- Issue comment#3anonimoustt2024-02-09 21:12is it possible to get the importance score of the protein sequence?
Totals cover only the window loaded into ClickHouse and count events, not GitHub's lifetime totals — 47 stars here means stars gained during the window, not the repo's star count.