AutoGrow4 is an open-source program for semi-automated computer-aided drug discovery. It uses a genetic algorithm to evolve predicted ligands on demand and so is not limited to a virtual library of pre-enumerated compounds. AutoGrow4 is a useful tool for generating entirely novel drug-like molecules and for optimizing preexisting ligands.
active 2023-08-31 → 2026-09-18 (UTC)
Activity over time
Daily event counts in the loaded window
Line chart, 1115 days from 2023-08-31 to 2026-09-18. Pushes: 222 total, peak 11 in a day. Pull requests: 40 total, peak 5 in a day. Issues: 16 total, peak 4 in a day. Comments: 3 total, peak 1 in a day. Stars: 46 total, peak 2 in a day.
- Pushes
- Pull requests
- Issues
- Comments
- Stars
Stars, PRs, issues and forks are under-captured in the later part of this window. GH Archive progressively stopped capturing non-push events during 2026 — −95% or worse by the end of the window. Every series here except Pushes fades for that reason, so a decline above reflects the archive, not this repository. Pushes stay reliable throughout, so read them, and the contributor counts derived from them, as the real signal. Data health has the measurements.
Top contributors
Pushes, PRs, issues, reviews and comments — stars and forks excluded, so this is contribution rather than popularity
| Contributor | Contributions | Pushes | PRs | Comments |
|---|---|---|---|---|
| jacobdurrant | 225 | 184 | 39 | 1 |
| crjacas | 40 | 37 | 0 | 0 |
| ElieC01 | 4 | 0 | 0 | 0 |
| TommyBiomodellingAU | 3 | 0 | 0 | 1 |
| sathishdasari | 3 | 0 | 0 | 0 |
| MayarMAhmed | 2 | 0 | 0 | 0 |
| gsuchunli | 1 | 0 | 0 | 0 |
| aalexmmaldonado | 1 | 1 | 0 | 0 |
| steverweber | 1 | 0 | 1 | 0 |
| jaketanderson | 1 | 0 | 0 | 1 |
Recent activity
Latest issues, pull requests and releases
Totals cover only the window loaded into ClickHouse and count events, not GitHub's lifetime totals — 46 stars here means stars gained during the window, not the repo's star count.