微软开源EvoDiff： 新一代蛋白质生成式AI Generation of protein sequences and evolutionary alignments via discrete diffusion models
Python · active 2023-09-12 → 2026-04-23 (UTC)
Activity over time
Daily event counts in the loaded window
Line chart, 955 days from 2023-09-12 to 2026-04-23. Pushes: 9 total, peak 6 in a day. Pull requests: 4 total, peak 1 in a day. Issues: 29 total, peak 3 in a day. Comments: 29 total, peak 6 in a day. Stars: 487 total, peak 39 in a day.
- Pushes
- Pull requests
- Issues
- Comments
- Stars
Stars, PRs, issues and forks are under-captured in the later part of this window. GH Archive progressively stopped capturing non-push events during 2026 — −95% or worse by the end of the window. Every series here except Pushes fades for that reason, so a decline above reflects the archive, not this repository. Pushes stay reliable throughout, so read them, and the contributor counts derived from them, as the real signal. Data health has the measurements.
Top contributors
Pushes, PRs, issues, reviews and comments — stars and forks excluded, so this is contribution rather than popularity
| Contributor | Contributions | Pushes | PRs | Comments |
|---|---|---|---|---|
| sarahalamdari | 11 | 4 | 1 | 3 |
| colbyford | 6 | 0 | 1 | 4 |
| PodevynLoris | 5 | 0 | 0 | 3 |
| microsoft-github-policy-service[bot] | 4 | 0 | 0 | 4 |
| nityathakkar | 4 | 4 | 0 | 0 |
| zhang-bo-lilly | 4 | 0 | 0 | 3 |
| yangkky | 3 | 0 | 0 | 2 |
| falcooon | 3 | 0 | 0 | 2 |
| JonathanDZiegler | 2 | 0 | 1 | 0 |
| marjanUofT | 2 | 0 | 0 | 1 |
| jasonkyuyim | 2 | 0 | 0 | 1 |
| JiangLab2020 | 2 | 0 | 0 | 1 |
| sherryliu987 | 2 | 0 | 0 | 2 |
| whypepper | 2 | 0 | 0 | 0 |
| violet-sto | 1 | 0 | 0 | 0 |
| brycejoh16 | 1 | 0 | 0 | 1 |
| BSharmi | 1 | 0 | 0 | 0 |
| YusenZheng | 1 | 0 | 0 | 0 |
| jsteward2930 | 1 | 0 | 0 | 0 |
| JisungJang-AI-BIO | 1 | 0 | 0 | 0 |
Recent activity
Latest issues, pull requests and releases
- Pull request#64sarahalamdari2026-01-15 21:51
- Issue#62sarahalamdari2025-07-10 17:55before version
- Issue#63whypepper2025-06-11 04:32EvoDiff scaffolding performance lower than expected on motif tasks
- Issue#63whypepper2025-06-08 15:42EvoDiff scaffolding performance lower than expected on motif tasks
- Issue comment#60codeamt2025-05-29 00:59cannot import name 'filter_backbone' from 'biotite.structure'
- Issue#62falcooon2025-05-14 03:03before version
- Issue comment#56falcooon2025-05-14 02:53Conditional Sequence Generation example command throwing an error
- Issue comment#37falcooon2025-05-14 02:50Non-canonical amino acid sequence seen
- Issue#60minhphi17122025-02-15 10:54cannot import name 'filter_backbone' from 'biotite.structure'
- Issue#59JisungJang-AI-BIO2024-12-31 02:00Custom a3m and pdb - Scaffolding functional motifs from an EvoDiff-MSA
- Issue#55JiangLab20202024-10-30 08:10How can I fine-tune the models with my sequences or MSAs?
- Issue comment#18JiangLab20202024-10-30 08:05Question about fine-tuning
- Issue comment#50colbyford2024-10-05 14:38The python version does not correspond to the version of the package required in evodiff
- Issue comment#50sarahalamdari2024-09-30 20:23The python version does not correspond to the version of the package required in evodiff
- Issue#47sarahalamdari2024-09-30 20:20conditional_generation inpaint import error
- Issue comment#47sarahalamdari2024-09-30 20:20conditional_generation inpaint import error
- Issue#51sarahalamdari2024-09-30 20:19Biotite v1.0.0 breaks conditional diffusion functions.
- Issue comment#51sarahalamdari2024-09-30 20:19Biotite v1.0.0 breaks conditional diffusion functions.
- Issue comment#52microsoft-github-policy-service[bot]2024-09-30 19:11Generate_msa --start-query for custom file
- Pull request#52rostro362024-09-30 19:11
- Issue#51colbyford2024-09-30 00:51Biotite v1.0.0 breaks conditional diffusion functions.
- Issue comment#47ranaabarghout2024-09-26 16:12conditional_generation inpaint import error
- Issue#50YusenZheng2024-09-26 12:49The python version does not correspond to the version of the package required in evodiff
- Issue#49diossynvax2024-09-26 12:30Using a novel config file in EvoDiff-MSA
- Issue comment#48zhang-bo-lilly2024-09-21 19:54Question about generating IDRs from EvoDiff-Seq
Totals cover only the window loaded into ClickHouse and count events, not GitHub's lifetime totals — 487 stars here means stars gained during the window, not the repo's star count.