regenie is a C++ program for whole genome regression modelling of large genome-wide association studies.
active 2023-08-15 → 2026-06-12 (UTC)
Activity over time
Daily event counts in the loaded window
Line chart, 1033 days from 2023-08-15 to 2026-06-12. Pushes: 48 total, peak 8 in a day. Pull requests: 6 total, peak 1 in a day. Issues: 332 total, peak 13 in a day. Comments: 516 total, peak 21 in a day. Stars: 91 total, peak 3 in a day.
- Pushes
- Pull requests
- Issues
- Comments
- Stars
Stars, PRs, issues and forks are under-captured in the later part of this window. GH Archive progressively stopped capturing non-push events during 2026 — −95% or worse by the end of the window. Every series here except Pushes fades for that reason, so a decline above reflects the archive, not this repository. Pushes stay reliable throughout, so read them, and the contributor counts derived from them, as the real signal. Data health has the measurements.
Top contributors
Pushes, PRs, issues, reviews and comments — stars and forks excluded, so this is contribution rather than popularity
| Contributor | Contributions | Pushes | PRs | Comments |
|---|---|---|---|---|
| joellembatchou | 365 | 48 | 2 | 223 |
| Ojami | 35 | 0 | 0 | 32 |
| dvg-p4 | 18 | 0 | 1 | 11 |
| dvh13 | 15 | 0 | 0 | 8 |
| jerome-f | 14 | 0 | 0 | 8 |
| nikotzoumas | 13 | 0 | 0 | 8 |
| scienception | 12 | 0 | 0 | 7 |
| nshrine | 12 | 0 | 0 | 6 |
| Lloyd-LiuSiyi | 12 | 0 | 0 | 7 |
| GHawkes93 | 10 | 0 | 0 | 6 |
| igumnov-daniel | 8 | 0 | 0 | 6 |
| Isabella678 | 7 | 0 | 0 | 6 |
| hahahazimi | 7 | 0 | 0 | 2 |
| lindenb | 6 | 0 | 0 | 2 |
| hguturu | 6 | 0 | 0 | 4 |
| dianacornejo | 6 | 0 | 0 | 3 |
| solivehong | 6 | 0 | 0 | 3 |
| akhilpampana | 6 | 0 | 0 | 4 |
| LeahBoettger | 6 | 0 | 0 | 4 |
| genoplan-ian | 5 | 0 | 0 | 4 |
Recent activity
Latest issues, pull requests and releases
- Issue#682joellembatchou2026-04-07 13:32Imputation score in summary statistics
- Issue#686joellembatchou2026-04-07 13:03Use REGENIE for Baseline GWAS Analysis
- Issue comment#686joellembatchou2026-04-07 13:03Use REGENIE for Baseline GWAS Analysis
- Issue comment#518nshrine2026-03-19 11:48Fraction of genes have no gene_p results
- Issue comment#684nievergeltlab2026-03-02 22:06Inflation of beta-values from logistic analysis - it is version specific
- Issue#684nievergeltlab2026-03-02 20:53Inflation of beta-values from logistic analysis - it is version specific
- Issue#683adunkwu2026-02-22 21:18P-value inflation from Step 2
- Issue comment#524dvg-p42026-02-05 22:45Document output format with `--htp` flag for region-based regenie step 2
- Issue#524dvg-p42026-01-30 17:32Document output format with `--htp` flag for region-based regenie step 2
- Issue#676Nobuyuki-Enzan2025-12-31 15:01Conditional analysis with multiple variants
- Issue#674sinhanushka122025-12-15 21:31how to define minMAC for generic burden test?
- Issue#640joellembatchou2025-11-13 03:28SNP with low variance - with conditional analysis
- Issue#639joellembatchou2025-11-13 03:28--condition-file, possible bug
- Issue#651joellembatchou2025-11-13 03:27Identical Pval for LOG, SKAT and SKATO models of a same mask
- Issue#660joellembatchou2025-11-13 03:27Individual (per sampleID) burden score calculation
- Issue#670joellembatchou2025-11-13 03:26--sex-specific option
- Pull request#672dvg-p42025-11-07 04:46
- Issue#671dvg-p42025-11-06 17:01Feature request: Allow writing masks to plink2 (pgen) file format so that non-integer weighted genotypes can be captured
- Issue comment#530frahimov2025-11-01 04:20Genotyped data for step 1>1M variants
- Issue#670cindywen962025-10-24 20:38--sex-specific option
- Issue#664mnshgl01102025-10-22 08:09Incorrect low-variance error?
- Issue comment#664mnshgl01102025-10-22 08:09Incorrect low-variance error?
- Issue comment#664mnshgl01102025-10-20 12:54Incorrect low-variance error?
- Issue comment#658joellembatchou2025-10-18 18:04How to correctly specify --*Col --*ColList for REGENIE ❓
- Issue comment#629nandobonf2025-10-16 11:03Question Regarding the a1freq_controls
Totals cover only the window loaded into ClickHouse and count events, not GitHub's lifetime totals — 91 stars here means stars gained during the window, not the repo's star count.